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- HEALTH, Page 88Cancer from Germs
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- A stomach bug is linked to gastric tumors and ulcers
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- By Andrew Purvis
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- Could cancer be an infectious disease? In some cases the
- answer is at least partly yes. Viruses are thought to play a
- role in liver and uterine cancer and some forms of lymphoma. Now
- comes the news that bacteria may actually be a major culprit in
- the world's second most common malignancy: stomach cancer,
- which afflicts an estimated 700,000 a year worldwide.
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- In separate studies of 130,000 and 6,000 people, reported
- in the New England Journal of Medicine, researchers from
- Stanford and Kuakini Medical Center in Honolulu found that
- people infected with the bacterium Helicobacter pylori were
- three to six times as likely to develop stomach cancer over a
- 20-year period as those who were not infected. "This is not just
- a little risk we're talking about," says Stanford's Julie
- Parsonnet, though she points out that not everyone infected with
- the bacterium develops cancer. Indeed, the bug, which may enter
- the body through dirty water or human contact, is extremely
- common: it is present in the gut of 50% of Americans and of up
- to 90% of people in poorer regions of Asia and Latin America.
- Researchers believe chronic inflammation, caused by the
- bacterium, combines with other risk factors, including a salty
- diet low in fresh fruit and vegetables, to cause the cancer.
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- The nefarious H. pylori has also been linked to ulcers and
- gastritis -- inflammation of the stomach lining. Parsonnet and
- others believe that people with chronic duodenal ulcers should
- consider a course of antibiotics to knock out the bug rather
- than rely on costly medications like Tagamet and Zantac, which
- treat the symptoms, not the cause. Meanwhile, studies are under
- way in Colombia and Mexico to determine if a similar strategy
- of antibiotics could play a role in cutting the world's
- incidence of stomach cancer.
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- THE WORLD'S MOST COMMON FORMS OF CANCER
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- 1. Lung
- 2. Stomach
- 3. Breast
- 4. Colon/Rectum
- 5. Cervix
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